What is Semaglutide?
Semaglutide is a compound belonging to the drug class known as glucagon-like peptide-1 (GLP-1) receptor agonists. It mimics a hormone called GLP-1 that is released naturally by the body after eating. GLP-1 slows digestion and signals the pancreas to produce insulin.
As an injectable GLP-1 receptor agonist, semaglutide likewise targets receptors to stimulate the release of insulin, which allows better blood sugar control.
It also decreases appetite, slows emptying of the stomach, and improves satiety.
The use of semaglutide for medical purposes first came about in the 2010s after being developed by the pharmaceutical company Novo Nordisk.In 2017, semaglutide received FDA approval for treating type 2 diabetes. A few years later in 2021, the FDA approved a higher dose of semaglutide specifically for chronic weight management in patients with obesity.